Molecular structure of deoxyribose nucleic acid
Molecular structure of deoxypentose nucleic acids.
Molecular structure of nucleic acids: a structure for deoxyribose nucleic acid
Learn how and when to remove this template message It is not always the case that the structure of a molecule is easy to relate to its function. Publication of this paper initiated the science of molecular biology. Offprint from Scientific American, October Crick 1 April 25, 2 , Nature 3 , , We wish to suggest a structure for the salt of deoxyribose nucleic acid D. A structure for nucleic acid has already been proposed by Pauling 4 and Corey1. It was a mistake. Their competitive spirit drove them to work quickly, and it undoubtedly helped them succeed in their quest. This copy is signed by all participants except Franklin and Watson. The hydrogens were part of the hydrogen bonds that held together the three intertwined chains. Original printed wrappers. These pairs are: adenine purine with thymine pyrimidine , and guanine purine with cytosine pyrimidine 9. This structure has two helical chains each coiled round the same axis see diagram. These were his starting points for a preliminary look at DNA. Watson and Crick's discovery of the double-helical structure of DNA is the most important medical and biological discovery of the twentieth century. In fact, the very next year, he would win the Nobel Prize in Chemistry — the first of his two Nobel Prizes.
Aware of these profound implications, Watson and Crick were obsessed with the problem—and, perhaps more than any other scientists, they were determined to find the answer first.
The planes of the bases are perpendicular to the fibre axis. The double helix describing the molecular structure of DNA has not only reshaped biology, it has become a cultural icon, represented in sculpture, visual art, jewellery, and toys.
According to science historian Victor McElheny of the Massachusetts Institute of Technology, this date was a turning point in a longstanding struggle between two camps of biology, vitalism and reductionism. This structure has two helical chains each coiled round the same axis see diagram.
The base pairs are held together by hydrogen bondsa type of chemical attraction that is easy to break and easy to reform. Garrison-Morton
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